Implantable MEMs for Drug Delivery

نویسندگان

  • H. L. Ho Duc
  • R. S. Langer
  • M. J. Cima
چکیده

Figure 1: Photographs showing (A) top and bottom of the silicon microchip, and (B) a packaged device with wire-bonded connector We have developed an implantable silicon microelectromechanical system (MEMS) device for biomedical applications [1]. This device contains an array of wells that hermetically store its contents. Activation of the device electrochemically dissolves gold membranes covering the wells, by application of an anodic voltage through a wire-bonded connector (Figure 1). The well contents are then exposed to the surrounding environment. This system allows temporal control of several activations and the ability to store a variety of contents separately. Targeted application for this device is local drug delivery.

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تاریخ انتشار 2005